Acekard-2i official team has released a Acekard-2i beta update patch for 3DS V4.3.0-10, with this patch, we can update our acekard-2i to work on the latest 3DS V4.3.0-10. i have tested this file, it is working and my ak2i can work on my 3DS V4.3.0-10 now.
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Source:
http://blog.digimartz.com/acekard-2i-supports-3ds-v4-3-0-10-now/